DM : somogyi effect vs dawn phenomenon

 somogyi effect: hypoglycemia at night , followed by rebound hyperglycemia in the morning , hypoglycemia due to so much insulin trigger release of counter regulatory hormones(epinephrine , glucagon,GH,cortisol ,all of them promote hepatic secretion of glucose and induce transient insulin resistance) 

Treatment  : decrease insulin(evening dose) dose or change time of administration


dawn phenomenon : early morning hyperglycemia and there is no hypoglycemia at night , appears to be the effect of growth hormones , increased liver glucose production , decrease peripheral tissue use 

Treatment :increase insulin dose (increase basal insulin ) or adjust timing to improve control

the most important !

how to differentiate :

check blood glucose at middle of night  , high or normal indicate dawn , low sugar indicate somogyi 

 

Mnemonic : 

somogyi : so much insulin 

dawon : down insulin(low insulin)

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